Cat: PA2000-9818

Recombinant Human NUFIP1 Protein,His

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Analytical Data

  • Gene name

    NUFIP1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    NUFIP1; Nuclear fragile X mental retardation-interacting protein 1; Nuclear FMRP-interacting protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9UHK0

  • Expression Region

    1-495 aa

  • AA Sequence

    MAEPTSDFET PIGWHASPEL TPTLGPLSDT APPRDSWMFW AMLPPPPPPL TSSLPAAGSK PSSESQPPME AQSLPGAPPP FDAQILPGAQ PPFDAQSPLD SQPQPSGQPW NFHASTSWYW RQSSDRFPRH QKSFNPAVKN SYYPRKYDAK FTDFSLPPSR KQKKKKRKEP VFHFFCDTCD RGFKNQEKYD KHMSEHTKCP ELDCSFTAHE KIVQFHWRNM HAPGMKKIKL DTPEEIARWR EERRKNYPTL ANIERKKKLK LEKEKRGAVL TTTQYGKMKG MSRHSQMAKI RSPGKNHKWK NDNSRQRAVT GSGSHLCDLK LEGPPEANAD PLGVLINSDS ESDKEEKPQH SVIPKEVTPA LCSLMSSYGS LSGSESEPEE TPIKTEADVL AENQVLDSSA PKSPSQDVKA TVRNFSEAKS ENRKKSFEKT NPKRKKDYHN YQTLFEPRTH HPYLLEMLLA PDIRHERNVI LQCVRYIIKK DFFGLDTNSA KSKDV

  • Molecular Weight

    56.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NUFIP1 (nuclear factor interacting with NAP1 protein 1) is a crucial component in the regulation of cellular processes, particularly in the context of chromatin remodeling and gene expression. It has been implicated in various biological functions, including DNA repair, transcriptional regulation, and cellular responses to stress. Research into NUFIP1 has gained momentum due to its potential roles in cancer biology and other diseases. Studies have shown that alterations in NUFIP1 expression can influence tumor growth and development, making it a valuable target for therapeutic interventions. The recombinant protein of NUFIP1 is essential for elucidating its structural and functional properties, enabling researchers to investigate its interactions with other molecular partners and its role in cellular pathways. Moreover, investigating the recombinant form allows for the development of assays to screen for small molecules that can modulate its activity, providing a basis for drug discovery. Overall, the study of NUFIP1 and its recombinant protein offers significant insights into its biological importance and potential as a therapeutic target, laying the groundwork for future research aimed at understanding its role in health and disease.

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