Analytical Data
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Gene name
NUPL2
- Application
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Alternative Names
NUP42; CG1; NUPL2; Nucleoporin NUP42; NLP-1; NUP42 homolog; Nucleoporin hCG1; Nucleoporin-42; Nucleoporin-like protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15504
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Expression Region
1-423 aa
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AA Sequence
MAICQFFLQG RCRFGDRCWN EHPGARGAGG GRQQPQQQPS GNNRRGWNTT SQRYSNVIQP SSFSKSTPWG GSRDQEKPYF SSFDSGASTN RKEGFGLSEN PFASLSPDEQ KDEKKLLEGI VKDMEVWESS GQWMFSVYSP VKKKPNISGF TDISPEELRL EYHNFLTSNN LQSYLNSVQR LINQWRNRVN ELKSLNISTK VALLSDVKDG VNQAAPAFGF GSSQAATFMS PGFPVNNSSS DNAQNFSFKT NSGFAAASSG SPAGFGSSPA FGAAASTSSG ISTSAPAFGF GKPEVTSAAS FSFKSPAASS FGSPGFSGLP ASLATGPVRA PVAPAFGGGS SVAGFGSPGS HSHTAFSKPS SDTFGNSSIS TSLSASSSII ATDNVLFTPR DKLTVEELEQ FQSKKFTLGK IPLKPPPLEL LNV
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Molecular Weight
44.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NUPL2, a member of the nucleoporin family, plays a critical role in the nuclear pore complex (NPC) and is involved in various cellular processes, including nucleocytoplasmic transport, gene expression regulation, and maintenance of nuclear integrity. Recent studies have highlighted the significance of NUPL2 in tumor biology, as it has been implicated in cancer progression and metastasis. Given its essential functions, the recombinant expression of NUPL2 has become a focal point in molecular biology research. The ability to produce large quantities of purified NUPL2 protein enables detailed biochemical and structural studies, allowing researchers to investigate its interactions with other nucleoporins and transport factors. Understanding the structural basis of NUPL2's function could provide insights into its role in oncogenesis and open avenues for the development of therapeutic strategies targeting nuclear transport mechanisms in cancer cells. Furthermore, the exploration of NUPL2's post-translational modifications may shed light on the regulatory mechanisms governing its activity and stability. Overall, NUPL2 serves as a promising target for research aimed at unraveling the complexities of nucleocytoplasmic transport and its implications in health and disease.
