Cat: PA2000-5315

Recombinant Human ABRA Protein,His

  • Price
  • Size
  • Number

    Order now. For delivery time, please consult customer service

  • Pre-sale guidance and worry-free after-sale service
  • Quality assurance for cold chain transportation

Analytical Data

  • Gene name

    ABRA

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ABRAActin-binding Rho-activating Protein; Striated muscle activator of Rho-dependent signaling; STARS

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8N0Z2

  • Expression Region

    1-381aa

  • AA Sequence

    MAPGEKESGE GPAKSALRKI RTATLVISLA RGWQQWANEN SIRQAQEPTG WLPGGTQDSP QAPKPITPPT SHQKAQSAPK SPPRLPEGHG DGQSSEKAPE VSHIKKKEVS KTVVSKTYER GGDVSHLSHR YERDAGVLEP GQPENDIDRI LHSHGSPTRR RKCANLVSEL TKGWRVMEQE EPTWRSDSVD TEDSGYGGEA EERPEQDGVQ VAVVRIKRPL PSQVNRFTEK LNCKAQQKYS PVGNLKGRWQ QWADEHIQSQ KLNPFSEEFD YELAMSTRLH KGDEGYGRPK EGTKTAERAK RAEEHIYREM MDMCFIICTM ARHRRDGKIQ VTFGDLFDRY VRISDKVVGI LMRARKHGLV DFEGEMLWQG RDDHVVITLL K

  • Molecular Weight

    43.1 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

Related Products

Protein Description

ABRA (Alpha-Actinin-Binding Protein) is a crucial member of the spectrin-repeat protein family, primarily involved in the regulation of actin cytoskeleton dynamics in various cellular contexts. Its significance lies in its ability to interact with alpha-actinin, a key actin-binding protein, thereby influencing muscle contraction, cellular motility, and the integrity of the cytoskeleton. Research has unveiled that ABRA plays an essential role in several physiological processes, including muscle development and repair, as well as the formation of specialized cellular structures. Additionally, aberrant ABRA function has been associated with various pathologies, including cancer, where it may contribute to tumor metastasis through its effects on cell migration and invasion. Recent advances in proteomics and molecular biology have facilitated a deeper understanding of ABRA’s structural characteristics and regulatory mechanisms, making it a focal point for studies aimed at unraveling its multifaceted roles in cell biology. The exploration of ABRA's function and interaction with other cellular components holds promise for the development of therapeutic strategies targeting diseases related to cytoskeletal dysregulation. This research not only helps decipher ABRA's involvement in fundamental cellular processes but also opens avenues for novel interventions in conditions where ABRA is implicated, highlighting its potential as a biomarker or therapeutic target in cancer and other disorders.

E-mail

sales@ipodix.com

Sales

+1 2092920560


Contact us via WhatsApp

IPODIX Biotech Inc

2108 N ST, STE N
Sacramento, CA 95816, USA

For Product Information and Orders

sales@ipodix.com

For Business Collaboration

sales@ipodix.com

For CRO Services

sales@ipodix.com

For Technical Support

sales@ipodix.com
  • 50000+

    Recombinant Proteins

  • 100+

    Researchers

  • 100+

    Countries Served

  • ISO

    Certified Quality

Committed to Quality
Driven by Innovation

Learn More About US