Cat: PA2000-9827

Recombinant Human NXNL1 Protein,His

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Analytical Data

  • 基因名

    NXNL1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    NXNL1; TXNL6; Nucleoredoxin-like protein 1; Thioredoxin-like protein 6

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q96CM4

  • 表达区间

    1-212 aa

  • 氨基酸序列

    MASLFSGRIL IRNNSDQDEL DTEAEVSRRL ENRLVLLFFG AGACPQCQAF VPILKDFFVR LTDEFYVLRA AQLALVYVSQ DSTEEQQDLF LKDMPKKWLF LPFEDDLRRD LGRQFSVERL PAVVVLKPDG DVLTRDGADE IQRLGTACFA NWQEAAEVLD RNFQLPEDLE DQEPRSLTEC LRRHKYRVEK AARGGRDPGG GGGEEGGAGG LF

  • 分子量

    23.9 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NXNL1 (Neural Retina Leucine Zipper Protein 1) is a gene that encodes a protein involved in various cellular processes, particularly in the retinal health and function of photoreceptors. It has garnered significant interest due to its potential role in retinal degenerative diseases, such as retinitis pigmentosa and age-related macular degeneration, conditions that result in vision loss. Research indicates that NXNL1 is crucial for maintaining the integrity of photoreceptor cells and protecting them from oxidative stress. Mutations in the NXNL1 gene have been associated with visual impairment, making it a target for therapeutic interventions. The study of NXNL1 recombinant proteins has been essential in elucidating its functional mechanisms and signaling pathways, paving the way for the development of gene therapies and protein replacement strategies. Recombinant NXNL1 proteins allow researchers to explore the interactions with other cellular components and assess their protective effects on retinal cells in vitro and in vivo. Additionally, understanding the structure and function of NXNL1 can lead to insights into its role in regulating gene expression and protein interactions in the retina, contributing to the overall understanding of retinal health and disease. As the field of gene therapy for retinal diseases advances, NXNL1 represents a promising candidate for future treatments aiming to restore or preserve vision in affected patients.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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