Analytical Data
-
Gene name
ABTB1
- Application
-
Alternative Names
ABTB 1; Abtb1; ABTB1_HUMAN; Ankyrin repeat and BTB (POZ) domain containing 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q969K4
-
Expression Region
1-478aa
-
AA Sequence
MDTSDLFASC RKGDVGRVRY LLEQRDVEVN VRDKWDSTPL YYACLCGHEE LVLYLLANGA RCEANTFDGE RCLYGALSDP IRRALRDYKQ VTASCRRRDY YDDFLQRLLE QGIHSDVVFV VHGKPFRVHR CVLGARSAYF ANMLDTKWKG KSVVVLRHPL INPVAFGALL QYLYTGRLDI GVEHVSDCER LAKQCQLWDL LSDLEAKCEK VSEFVASKPG TCVKVLTIEP PPADPRLRED MALLADCALP PELRGDLWEL PFPCPDGFNS CPDICFRVAG CSFLCHKAFF CGRSDYFRAL LDDHFRESEE PATSGGPPAV TLHGISPDVF THVLYYMYSD HTELSPEAAY DVLSVADMYL LPGLKRLCGR SLAQMLDEDT VVGVWRVAKL FRLARLEDQC TEYMAKVIEK LVEREDFVEA VKEEAAAVAA RQETDSIPLV DDIRFHVAST VQTYSAIEEA QQRLRALEDL LVSIGLDC
-
Molecular Weight
53.9 KDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABTB1 (Ankyrin Repeat and BTB/POZ Domain Containing 1) is a protein that has garnered increasing interest in recent years due to its potential roles in various biological processes, including cellular signaling, protein degradation, and tumor suppression. As a member of the BTB-Kelch protein family, ABTB1 is characterized by the presence of ankyrin repeats and a BTB/POZ domain, which are instrumental in mediating protein-protein interactions. Research has indicated that ABTB1 may be involved in regulating the activity of key signaling pathways, thus influencing cell proliferation and apoptosis. Its expression patterns have been linked to several cancers, prompting investigations into its functional mechanisms and potential as a biomarker or therapeutic target. Furthermore, the exploration of ABTB1's structure and interactions through recombinant protein studies is crucial for understanding its role in health and disease. By producing and characterizing ABTB1 recombinant proteins, researchers aim to elucidate its cellular functions and develop strategies to modulate its activity in pathological contexts, ultimately contributing to advancements in cancer therapy and therapeutic interventions.
