Analytical Data
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基因名
STX17
- Application
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别名
STX17；Syntaxin-17
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P56962
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表达区间
1-229aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMSEDEEK VKLRRLEPAI QKFIKIVIPT DLERLRKHQI NIEKYQRCRI WDKLHEEHIN AGRTVQQLRS NIREIEKLCL KVRKDDLVLL KRMIDPVKEE ASAATAEFLQ LHLESVEELK KQFNDEETLL QPPLTRSMTV GGAFHTTEAE ASSQSLTQIY ALPEIPQDQN AAESWETLEA DLIELSQLVT DFSLLVNSQQ EKIDSIADHV NSAAVNVEEG TKNLGKAAKY KL
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分子量
29 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX17, a member of the syntaxin family of proteins, plays a crucial role in the trafficking and fusion of vesicles within cells, particularly in the context of autophagy and exocytosis. The importance of STX17 has been increasingly highlighted in recent years, as it is involved in the regulation of autophagic processes, which are vital for cellular homeostasis, nutrient recycling, and the response to stress. Dysfunction or dysregulation of STX17 has been implicated in various diseases, including neurodegenerative disorders and cancer, where impaired autophagy contributes to cellular dysfunction and disease progression. Research into STX17 recombinant protein has aimed to elucidate its molecular mechanisms, interactions with other autophagy-related proteins, and its potential as a therapeutic target. This recombinant protein is pivotal for in vitro studies, allowing scientists to dissect the pathways of vesicle trafficking and autophagic flux in a controlled environment. Understanding STX17's role within these pathways may lead to novel insights into how to manipulate autophagic processes for therapeutic benefit in diseases characterized by autophagy impairment. As such, STX17 recombinant protein serves as a valuable tool for both fundamental studies of cell biology and the development of targeted therapies in the context of diseases where STX17-related pathways are disrupted.
