Analytical Data
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Gene name
STX17
- Application
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Alternative Names
STX17；Syntaxin-17
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P56962
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Expression Region
1-229aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSEDEEK VKLRRLEPAI QKFIKIVIPT DLERLRKHQI NIEKYQRCRI WDKLHEEHIN AGRTVQQLRS NIREIEKLCL KVRKDDLVLL KRMIDPVKEE ASAATAEFLQ LHLESVEELK KQFNDEETLL QPPLTRSMTV GGAFHTTEAE ASSQSLTQIY ALPEIPQDQN AAESWETLEA DLIELSQLVT DFSLLVNSQQ EKIDSIADHV NSAAVNVEEG TKNLGKAAKY KL
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Molecular Weight
29 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STX17, a member of the syntaxin family of proteins, plays a crucial role in the trafficking and fusion of vesicles within cells, particularly in the context of autophagy and exocytosis. The importance of STX17 has been increasingly highlighted in recent years, as it is involved in the regulation of autophagic processes, which are vital for cellular homeostasis, nutrient recycling, and the response to stress. Dysfunction or dysregulation of STX17 has been implicated in various diseases, including neurodegenerative disorders and cancer, where impaired autophagy contributes to cellular dysfunction and disease progression. Research into STX17 recombinant protein has aimed to elucidate its molecular mechanisms, interactions with other autophagy-related proteins, and its potential as a therapeutic target. This recombinant protein is pivotal for in vitro studies, allowing scientists to dissect the pathways of vesicle trafficking and autophagic flux in a controlled environment. Understanding STX17's role within these pathways may lead to novel insights into how to manipulate autophagic processes for therapeutic benefit in diseases characterized by autophagy impairment. As such, STX17 recombinant protein serves as a valuable tool for both fundamental studies of cell biology and the development of targeted therapies in the context of diseases where STX17-related pathways are disrupted.
