Cat: PAX2000-10038

Recombinant Human ORAOV1 Protein,His

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Analytical Data

  • Gene name

    ORAOV1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    LTO1; ORAOV1; TAOS1Protein LTO1 homolog; Oral cancer-overexpressed protein 1; Tumor-amplified and overexpressed sequence 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8WV07

  • Expression Region

    2-137 aa

  • AA Sequence

    AGSQDIFDA IVMADERFHG EGYREGYEEG SSLGVMEGRQ HGTLHGAKIG SEIGCYQGFA FAWKCLLHSC TTEKDSRKMK VLESLIGMIQ KFPYDDPTYD KLHEDLDKIR GKFKQFCSLL NVQPDFKISA EGSGLSF

  • Molecular Weight

    15.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ORAOV1, or Ovarian Tumor Biomarker 1, is a protein that has garnered considerable attention due to its association with ovarian cancer and its potential role as a biomarker for diagnosis and treatment monitoring. Research indicates that ORAOV1 is overexpressed in ovarian tumors compared to normal ovarian tissues, making it a candidate for not only understanding the molecular mechanisms underlying ovarian cancer development but also for improving early detection strategies. As ovarian cancer often presents at an advanced stage and is associated with high mortality rates, identifying reliable biomarkers like ORAOV1 is crucial. Studies have shown that ORAOV1 may also be involved in promoting tumor growth and metastasis, which highlights its significance in cancer biology. The recombinant expression of ORAOV1 protein enables researchers to investigate its structure, function, and interactions at a molecular level, facilitating the development of targeted therapies. Additionally, the production of recombinant ORAOV1 can aid in the development of serological assays for cancer detection, contributing to advancements in personalized medicine. Overall, the study of ORAOV1 represents a promising avenue for enhancing our understanding of ovarian cancer and improving clinical outcomes for patients.

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