Analytical Data
-
基因名
GAPDHS
- Application
-
别名
GAPDHS；GAPD2；GAPDH2；GAPDS；Glyceraldehyde-3-phosphate dehydrogenase. testis-specific
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O14556
-
表达区间
69-408aa
-
氨基酸序列
MVSVARELTVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSYTATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVSVVDLTCRLAQPAPYSAIKEAVKAAAKGPMAGILAYTEDEVVSTDFLGDTHSSIFDAKAGIALNDNFVKLISWYDNEYGYSHRVVDLLRYMFSRDK
-
分子量
39.1 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic) is a crucial enzyme primarily expressed in the testis, playing a pivotal role in male fertility through its involvement in glycolysis and energy metabolism during sperm development. Its unique nucleotide sequence and distinct regulatory mechanisms set it apart from the ubiquitous GAPDH isoforms found in other tissues. Recent research has highlighted the enzyme's potential beyond metabolism, suggesting roles in apoptosis, cellular signaling, and the regulation of gene expression. Given that disturbances in GAPDHS expression can lead to male infertility, the protein has emerged as a significant focus of study in reproductive biology. Researchers are particularly interested in the structural and functional characterization of GAPDHS to understand its specific contributions to spermatogenesis and to explore its potential as a biomarker for male reproductive health. Additionally, the development of GAPDHS recombinant proteins facilitates the study of its enzymatic properties and interactions with other cellular components, thereby paving the way for novel therapeutic approaches to address fertility issues. Understanding the functional dynamics of GAPDHS not only enriches our knowledge of sperm biology but also opens avenues for targeted interventions in cases of unexplained infertility.
