Analytical Data
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基因名
PLAG1
- Application
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别名
Zinc finger protein PLAG1. Pleiomorphic adenoma gene 1 protein
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6DJT9
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表达区间
1-500 aa
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氨基酸序列
MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ
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分子量
55 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLAG1 (pleomorphic adenoma gene 1) is a transcription factor known to play a crucial role in cell growth, differentiation, and oncogenesis. It is primarily associated with pleomorphic adenoma, a common benign tumor of the salivary glands, where PLAG1 gene rearrangements often lead to its overexpression. Research into PLAG1-recombinant proteins has gained momentum due to their potential implications in cancer biology and therapeutic applications. Understanding the structural and functional characteristics of PLAG1 can provide insights into its role in tumorigenesis and cellular signaling pathways. Moreover, PLAG1 can serve as a valuable biomarker for diagnosing related neoplasms. The development of PLAG1-recombinant proteins enables the exploration of its biochemical activity, interactions with other cellular proteins, and regulatory mechanisms. This research not only furthers the understanding of salivary gland tumors but may also uncover broader implications for other cancers driven by transcriptional dysregulation. Overall, the study of PLAG1-recombinant proteins is critical for developing diagnostic tools and targeted therapies, addressing the urgent need for advancements in cancer treatment strategies.
