Analytical Data
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基因名
Cd300a
- Application
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别名
Cd300a；CMRF35H；CMRF35-like molecule 8
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UGN4
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表达区间
18-178aa
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氨基酸序列
LSKCRTVAGPVGGSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGS AGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPV VEVEVSVFPASTSMTPASITAAKTSTITTAFPPVSSTTLFAVGATHSASI QEETEEVVNSQVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPP KPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQ YNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPRE PQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTP PVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSP GKHHHHHH
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分子量
45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD300a, a member of the CD300 gene family, is an immune receptor primarily expressed on myeloid cells, including monocytes, macrophages, and dendritic cells. Its role in immune regulation has become a significant area of research due to its potential implications in various diseases, including autoimmune disorders, infections, and cancer. CD300a is known to interact with phosphatidylserine and other ligands, thereby influencing cell signaling pathways involved in immune responses. Recent studies have highlighted its ability to modulate the activation and differentiation of immune cells, suggesting that CD300a may serve as a critical regulator of immune homeostasis. The development of recombinant CD300a protein allows researchers to investigate its biological functions in detail and explore its potential as a therapeutic target. By studying this protein, scientists aim to elucidate the mechanisms underlying its immunoregulatory functions, which may lead to novel strategies for manipulating immune responses in various pathological contexts. Furthermore, understanding CD300a's signaling pathways could open new avenues for the design of interventions to enhance anti-tumor immunity or mitigate excessive inflammatory responses. Overall, research on recombinant CD300a protein represents a promising frontier in the field of immunology, with implications for advancing therapeutic approaches in immune-related diseases.
