Analytical Data
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基因名
BXDC5
- Application
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别名
RPF1; BXDC5; Ribosome production factor 1; Brix domain-containing Protein 5; Ribosome biogenesis Protein RPF1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H9Y2
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表达区间
1-349aa
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氨基酸序列
MAKAGDKSSS SGKKSLKRKA AAEELQEAAG AGDGATENGV QPPKAAAFPP GFSISEIKNK QRRHLMFTRW KQQQRKEKLA AKKKLKKERE ALGDKAPPKP VPKTIDNQRV YDETTVDPND EEVAYDEATD EFASYFNKQT SPKILITTSD RPHGRTVRLC EQLSTVIPNS HVYYRRGLAL KKIIPQCIAR DFTDLIVINE DRKTPNGLIL SHLPNGPTAH FKMSSVRLRK EIKRRGKDPT EHIPEIILNN FTTRLGHSIG RMFASLFPHN PQFIGRQVAT FHNQRDYIFF RFHRYIFRSE KKVGIQELGP RFTLKLRSLQ KGTFDSKYGE YEWVHKPREM DTSRRKFHL
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分子量
40.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BXDC5 is a protein that has garnered significant attention in the field of biotechnology and pharmaceutical research due to its potential roles in immune modulation and disease intervention. Initially identified through genomic studies focused on immune-related genes, BXDC5 is part of a larger family of proteins involved in the regulation of immune responses, particularly in the context of autoimmune diseases and cancer. The structural features of BXDC5 suggest that it may interact with specific receptors on immune cells, thereby influencing their activation and function. Research has indicated that recombinant forms of BXDC5 can enhance the proliferation and activation of T-cells and other immune effector cells, making it a candidate for therapeutic applications. Moreover, studies are exploring its potential as a biomarker for diseases where immune dysregulation is a hallmark. Ongoing investigations aim to elucidate the precise mechanisms by which BXDC5 exerts its effects, which could pave the way for innovative strategies in immunotherapy. As our understanding of this protein advances, its implications for enhancing vaccine responses and developing new immunotherapeutic agents may revolutionize treatment approaches for various immune-related disorders.












