Analytical Data
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基因名
C14orf1
- Application
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别名
ERG28; C14orf1; AD-011; HSPC288; x0006; Ergosterol biosynthetic Protein 28 homolog
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UKR5
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表达区间
1-140 aa
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氨基酸序列
MSRFLNVLRSWLVMVSIIAMGNTLQSFRDHTFLYEKLYTGKPNLVNGLQARTFGIWTLLSSVIRCLCAIDIHNKTLYHITLWTFLLALGHFLSELFVYGTAAPTIGVLAPLMVASFSILGMLVGLRYLEVEPVSRQKKRN
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分子量
42.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C14orf1, also known as TCEAL1 (T-cell acute lymphocytic leukemia 1), has gained attention in recent years due to its potential roles in various biological processes, including cell cycle regulation, apoptosis, and immune response modulation. This protein is located on chromosome 14 and is associated with several cellular functions, particularly in T-cells where its expression is upregulated during activation. Research indicates that C14orf1 may be involved in the pathogenesis of certain cancers, particularly T-cell malignancies, making it a target for therapeutic exploration. Its function as a transcriptional regulator is also being studied, particularly concerning its interactions with other proteins and DNA elements that modulate gene expression. The recombinant expression of C14orf1 allows for better understanding of its biochemical properties, structure-function relationship, and molecular mechanisms. Through techniques such as protein purification and characterization, researchers aim to elucidate the role of C14orf1 in cellular signaling pathways and its potential as a biomarker for diseases. The ongoing investigation into C14orf1 is crucial for developing novel diagnostic and therapeutic strategies, particularly in oncology and immunology.
