Analytical Data
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基因名
RTBDN
- Application
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别名
RTBDN;Retbindin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BSG5
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表达区间
31-229aa
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氨基酸序列
SRPLQARSQQHHGLAADLGKGKLHLAGPCCPSEMDTTETSGPGNHPERCG VPSPECESFLEHLQR ALRSRFRLRLLGVRQAQPLCEELCQAWFANCEDDITCGPTWLPLSEKRGC EPSCLTYGQTFADGT DLCRSALGHALPVAAPGARHCFNISISAVPRPRPGRRGREAPSRRSRSPR TSILDAAGSGSGSGS GSGPVDHHHHHH
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RTBDN (Regulator of Transcription and DNA Damage Response), a protein implicated in various cellular processes, has garnered significant attention in recent years due to its roles in regulating transcription and responding to DNA damage. As a crucial player in maintaining genomic stability, RTBDN is believed to facilitate the orchestration of molecular pathways that govern cell cycle progression, DNA repair mechanisms, and gene expression. Dysregulation of RTBDN has been associated with several diseases, including cancer, where it may contribute to aberrant cell proliferation and survival. Research has increasingly focused on elucidating the mechanistic functions of RTBDN and its interactions with other proteins involved in the DNA damage response. Understanding RTBDN's structure-function relationship and its regulatory mechanisms could pave the way for novel therapeutic strategies targeting its pathways, particularly in cancer treatment. Furthermore, studies utilizing recombinant RTBDN allow for the exploration of its biochemical properties, interaction networks, and functional domains in a controlled setting, providing vital insights into its contribution to cellular homeostasis and disease pathology. As research progresses, unraveling the complexities of RTBDN will be essential for developing targeted interventions that can enhance the body's ability to manage DNA damage and improve therapeutic outcomes for patients with related disorders.












