Analytical Data
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Gene name
C17orf57
- Application
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Alternative Names
EFCAB13; C17orf57EF-hand calcium-binding domain-containing Protein 13
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IY85
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Expression Region
1-531aa
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AA Sequence
MENDDLESKRPKNTWQIRKFLGGVGSSNVGVQEPYSKNGINFKKHSEKGEIHDSKSKPQSLKSSTSLSKSLDKSDISSIPKLQKPAVRKHSSLQKQVSSTEKTAISTLENFCEAISKLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMVELDDFVNALAKERSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFKKITELTEAGETKKVNFKEFIDTMMSNTECFSEKLVLPDAIETLDDLRKETMSVSDLWNTLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVRNMRDAARLEELQEVVLAADLLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIKDCMRALRDTQKFSNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFNEALNCCNVSDNMEVDLKDFLMKMKESPHFQKSKATQILLATTQILQNDLVDVSDLKTLLMDKDLHTANAILTVMLRHVPEHG
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Molecular Weight
86.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C17orf57, also known as Chromosome 17 Open Reading Frame 57, is a gene located on chromosome 17 that has garnered attention for its potential role in various biological processes and diseases. Initial studies suggested that C17orf57 might be involved in the regulation of cellular functions, including growth and apoptosis, making it a candidate for research in cancer biology. The protein encoded by C17orf57 exhibits significant conservation across species, indicating its potential importance in fundamental biological mechanisms. Recent advances in proteomic and genomic technologies have facilitated the investigation of its structural characteristics and functional roles in cellular pathways. Moreover, the identification of potential interacting partners has raised interest in its involvement in complex cellular networks. Understanding the recombinant protein of C17orf57 may provide insights into its biological functions and its implications in disease contexts, particularly in malignancies where its expression levels might be altered. This exploration could lead to novel therapeutic strategies by targeting C17orf57-related pathways, enhancing our understanding of tumorigenesis and other disorders associated with chromosomal abnormalities. Therefore, characterizing C17orf57 and its recombinant protein is crucial for unraveling its biological significance and potential clinical applications.
