Analytical Data
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Gene name
RASSF2
- Application
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Alternative Names
CENP 34; Centromere protein 34; Ras association (RalGDS/AF 6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain containing protein 2; Ras association domain-containing protein 2; RASF2_HUMAN; RASFADIN; RASSF2; RP4-599I11.1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P50749
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Expression Region
1-326 aa
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AA Sequence
MDYSHQTSLV PCGQDKYISK NELLLHLKTY NLYYEGQNLQ LRHREEEDEF IVEGLLNISW GLRRPIRLQM QDDNERIRPP PSSSSWHSGC NLGAQGTTLK PLTVPKVQIS EVDAPPEGDQ MPSSTDSRGL KPLQEDTPQL MRTRSDVGVR RRGNVRTPSD QRRIRRHRFS INGHFYNHKT SVFTPAYGSV TNVRINSTMT TPQVLKLLLN KFKIENSAEE FALYVVHTSG EKQKLKATDY PLIARILQGP CEQISKVFLM EKDQVEEVTY DVAQYIKFEM PVLKSFIQKL QEEEDREVKK LMRKYTVLRL MIRQRLEEIA ETPATI
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Molecular Weight
37.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RASSF2 (Ras Association Domain Family Member 2) is a protein that plays a significant role in various cellular processes, including signal transduction and tumor suppression. Research has shown that RASSF2 is involved in the regulation of the cell cycle, apoptosis, and cellular response to stress, making it a crucial player in maintaining cellular homeostasis. It has been implicated in multiple types of cancer, where its expression levels can be altered. Understanding the mechanisms by which RASSF2 operates can provide vital insights into cancer biology and potential therapeutic targets. Recent studies have focused on the functional characterization of RASSF2 through the development of recombinant proteins, which allow for detailed investigations into its interactions and signaling pathways. By expressing RASSF2 as a recombinant protein, researchers aim to elucidate its role in oncogenic processes, explore its potential as a biomarker for cancer diagnosis and prognosis, and assess its viability as a target for novel therapeutic strategies. The knowledge gained from RASSF2 studies could pave the way for advancements in cancer treatment and contribute to the development of personalized medicine approaches.
