Analytical Data
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基因名
RBM34
- Application
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别名
KIAA0117; Rbm34; RBM34_HUMAN; RNA binding motif protein 34; RNA-binding motif protein 34; RNA-binding protein 34
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P42696
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表达区间
1-430 aa
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氨基酸序列
MALEGMSKRK RKRSVQEGEN PDDGVRGSPP EDYRLGQVAS SLFRGEHHSR GGTGRLASLF SSLEPQIQPV YVPVPKQTIK KTKRNEEEES TSQIERPLSQ EPAKKVKAKK KHTNAEKKLA DRESALASAD LEEEIHQKQG QKRKNSQPGV KVADRKILDD TEDTVVSQRK KIQINQEEER LKNERTVFVG NLPVTCNKKK LKSFFKEYGQ IESVRFRSLI PAEGTLSKKL AAIKRKIHPD QKNINAYVVF KEESAATQAL KRNGAQIADG FRIRVDLASE TSSRDKRSVF VGNLPYKVEE SAIEKHFLDC GSIMAVRIVR DKMTGIGKGF GYVLFENTDS VHLALKLNNS ELMGRKLRVM RSVNKEKFKQ QNSNPRLKNV SKPKQGLNFT SKTAEGHPKS LFIGEKAVLL KTKKKGQKKS GRPKKQRKQK
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分子量
48.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RBM34 (RNA-binding motif protein 34) is a member of the RNA-binding motif protein family, characterized by its role in post-transcriptional regulation of gene expression. Research into RBM34 has gained traction due to its potential implications in various biological processes, including cellular differentiation, proliferation, and apoptosis. The protein is known to interact with specific RNA sequences, influencing mRNA stability and translation, thereby impacting protein synthesis. Aberrant expression of RBM34 has been implicated in several diseases, particularly cancer, where it may contribute to tumorigenesis by modulating the expression of key oncogenes and tumor suppressor genes. Moreover, studies have suggested that RBM34 might play a role in the regulation of immune responses, as its expression is found to be modulated in various immune cell types. Investigating the structural and functional characteristics of recombinant RBM34 protein is essential for understanding its molecular mechanisms and could provide insights into its potential as a therapeutic target or biomarker in disease contexts. Experimental approaches, including the generation of recombinant RBM34 proteins, allow for detailed studies of its RNA-binding capabilities and effects on gene regulation, fostering a deeper understanding of its biological significance.
