Cat: PA2000-6420

Recombinant Human CACNG7 Protein,GST

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Analytical Data

  • 基因名

    CACNG7

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CACNG7; Voltage-dependent calcium channel gamma-7 subunit; Neuronal voltage-gated calcium channel gamma-7 subunit; Transmembrane AMPAR regulatory Protein gamma-7; TARP gamma-7

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P62955

  • 表达区间

    1-275aa

  • 氨基酸序列

    MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC

  • 分子量

    57.4 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CACNG7, a member of the calcium channel subunit family, plays a crucial role in the regulation of voltage-gated calcium channels (VGCCs) and synaptic transmission. It is known to act as a gamma subunit, modulating the channel's properties and influencing calcium influx in neurons. Aberrations in CACNG7 have been linked to various neurological disorders, illustrating its significance in neuronal communication and plasticity. Given its potential implications in the pathophysiology of conditions such as epilepsy, schizophrenia, and autism, the study of CACNG7 has garnered substantial interest in the field of neuroscience. Recent advancements in recombinant protein technology have enabled the production of purified CACNG7, facilitating the exploration of its structural and functional characteristics. By employing techniques like protein expression systems and subsequent purification methods, researchers aim to uncover the specific interactions between CACNG7 and VGCCs, as well as its impact on neuronal excitability. Understanding these mechanisms at the molecular level may provide new insights into therapeutic targets for treating neuropsychological disorders. Additionally, the study of CACNG7 could contribute to the broader understanding of calcium signaling in various cellular processes, enhancing our comprehension of both normal and pathological brain function. Therefore, ongoing research into recombinant CACNG7 protein holds promise for advancing our knowledge in neurobiology and developing innovative strategies for intervention in related diseases.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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