Analytical Data
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Gene name
CALM3
- Application
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Alternative Names
CALM3. CALML2. CAM3. CAMC. CAMIII
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P0DP25
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Expression Region
1-149aa
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AA Sequence
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
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Molecular Weight
42.02 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CALM3 (Calmodulin 3) is a member of the calmodulin family, which is a vital calcium-binding messenger protein expressed in all eukaryotic cells. Calmodulin plays a key role in various cellular processes by mediating calcium signaling pathways, and CALM3 specifically is implicated in several physiological functions, including muscle contraction, enzyme activation, and gene expression regulation. The importance of CALM3 in cellular signaling has led to extensive research, particularly in understanding its role in neurobiology and cardiovascular health. Abnormalities in CALM3 expression or function have been associated with various diseases, including cardiac disorders and neurological conditions. Therefore, the study of CALM3 recombinant proteins is crucial for elucidating its biochemical properties and interactions with various target proteins. By producing CALM3 in a recombinant system, researchers can investigate its ligand-binding characteristics, post-translational modifications, and functional implications in detail. This research has the potential to provide insights into the mechanisms underlying disease pathologies and to identify novel therapeutic targets. Additionally, the recombinant CALM3 protein can serve as a valuable tool in drug discovery, enabling high-throughput screening of potential calmodulin inhibitors or activators. Overall, the study of CALM3 recombinant protein is a significant endeavor that combines biochemistry, molecular biology, and pharmacology, addressing both fundamental scientific questions and practical medical applications.
