Analytical Data
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基因名
SLC25A33
- Application
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别名
SLC25A33; Solute carrier family 25 member 33; Bone marrow stromal cell mitochondrial carrier protein; BMSC-MCP; HuBMSC-MCP; Protein PNC1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BSK2
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表达区间
1-321 aa
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氨基酸序列
MATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ
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分子量
61.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC25A33, a member of the solute carrier family 25, plays a crucial role in mitochondrial transport processes, particularly in the transport of nucleotides and small molecules across the mitochondrial membrane. Recent studies have highlighted its involvement in various cellular functions, including energy metabolism, apoptosis, and the regulation of intracellular calcium levels. Aberrant expression or malfunction of SLC25A33 has been linked to several metabolic disorders and mitochondrial diseases, making it a significant target for therapeutic interventions. The recombinant expression of SLC25A33 in model systems allows for detailed investigation of its structural and functional properties, facilitating a better understanding of its role in cellular metabolism. Such research aims to elucidate the mechanisms by which SLC25A33 contributes to mitochondrial function and its implications in human health and disease. Additionally, understanding SLC25A33’s interactions with other mitochondrial proteins and its regulatory pathways could provide insights into potential drug targets for conditions associated with mitochondrial dysfunction. Thus, the recombinant protein of SLC25A33 serves as a valuable tool for advancing knowledge in mitochondrial biology and developing new therapeutic strategies.
