Analytical Data
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基因名
DCUN1D5
- Application
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别名
DCUN1D5DCN1-like protein 5; DCUN1 domain-containing protein 5; Defective in cullin neddylation protein 1-like protein 5
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BTE7
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表达区间
1-237aa
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氨基酸序列
MPVKKKRKSPGVAAAVAEDGGLKKCKISSYCRSQPPARLISGEEHFSSKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQNKFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPVLLDEFVEWQKVRQTS
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分子量
53.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DCUN1D5, a member of the DCUN1D protein family, is implicated in various cellular processes, primarily associated with the ubiquitin-proteasome system, which governs protein degradation and turnover. Research interests surrounding DCUN1D5 have surged due to its potential role in modulating protein homeostasis and contributing to disease mechanisms, particularly in cancer and neurodegenerative disorders. Initial studies suggest that DCUN1D5 may influence the stability and activity of key regulatory proteins, thereby affecting cell cycle progression and apoptosis. Given the importance of ubiquitin-mediated degradation in maintaining cellular health, understanding the precise molecular functions of DCUN1D5 could unveil novel therapeutic targets. Furthermore, its interactions with E3 ubiquitin ligases and potential involvement in protein quality control pathways position DCUN1D5 as a critical component in the study of proteostasis. As research advances, elucidating the specific mechanisms by which DCUN1D5 operates might provide insights into its roles in various pathological conditions, highlighting the significance of this protein in fundamental biological processes.
