Analytical Data
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Gene name
SCXB
- Application
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Alternative Names
SCXB;BHLHA41;BHLHA48;SCXA;Basic helix-loop-helix transcription factor scleraxis
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7RTU7
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Expression Region
1-201aa
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AA Sequence
MSFATLRPAP PGRYLYPEVS PLSEDEDRGS DSSGSDEKPC RVHAARCGLQ GARRRAGGRR AGGGGPGGRP GREPRQRHTA NARERDRTNS VNTAFTALRT LIPTEPADRK LSKIETLRLA SSYISHLGNV LLAGEACGDG QPCHSGPAFF HAARAGSPPP PPPPPPARDG ENTQPKQICT FCLSNQRKLS KDRDRKTAIR S
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SCXB, or subcutaneous fat cell-expressed protein B, is a member of the S100 protein family, which is known for its role in various cellular processes, including inflammation, cell differentiation, and apoptosis. Recent studies have highlighted its potential involvement in metabolic regulation and tissue homeostasis, particularly in the context of adipocyte function and obesity-related diseases. The dysregulation of SCXB has been linked to altered lipid metabolism and insulin resistance, making it a significant target for investigating therapeutic approaches for metabolic syndromes. Research has focused on characterizing the structure and function of SCXB, understanding its signaling pathways, and exploring its interaction with other proteins and cells in the adipose tissue microenvironment. Additionally, the examination of SCXB gene expression in various physiological and pathological conditions has provided insights into its role in obesity and related complications, such as Type 2 diabetes and cardiovascular diseases. The findings suggest that SCXB could serve as a biomarker for obesity and a potential therapeutic target, paving the way for new strategies in the management and treatment of metabolic disorders. Overall, the ongoing research into SCXB holds promise for advancing our understanding of fat biology and its implications for health and disease.











