Analytical Data
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基因名
TMCO7
- Application
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别名
TANGO6; KIAA1746; TMCO7; Transport and Golgi organization Protein 6 homolog; Transmembrane and coiled-coil domain-containing Protein 7
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9C0B7
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表达区间
1-334 aa
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氨基酸序列
MAARQAVGSGAQETCGLDRILEALKLLLSPGGSGSSSLQVTKHDVLLATLKSNLSALEDKFLKDPQWKNLKLLRDEIADKAEWPQNSVDVTWSFTSQTLLLLLCLKETMIRLAANFNPGKPNPRTPEVAPALSPDALSISQQKTVQFVLQFVVTLGICPYLMPGVGVPLRYRTEFGAVVQDVVCFDAAPDATRRLYTSCKALLNVAQHTSLGSLIFCHHFGDIAAGLCQLGFCPTKRKLLTPAEEVLTEEERTLSRGALRDMLDQVYQPLAVRELLILQGGPPQSCTDVKTQMRCRAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGGKK
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分子量
62.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMCO7, a member of the Transmembrane and Coiled-Coil Domains 7 (TMCO) protein family, has garnered increasing attention in the fields of molecular biology and biochemistry due to its potential role in cellular processes, particularly in the endoplasmic reticulum (ER) and calcium homeostasis. Research indicates that TMCO7 may be involved in the regulation of ion channels and the maintenance of ER calcium levels, which are critical for various physiological functions, including protein folding, signaling, and cell survival. The understanding of TMCO7 is still in its nascent stages; however, preliminary studies suggest that its dysfunction could be linked to certain diseases, making it a potential target for therapeutic intervention. Ongoing research aims to elucidate its specific functions, interactions, and mechanisms of action within the cell, with an emphasis on its structure-function relationship. The heterologous expression and characterization of TMCO7 as a recombinant protein are vital steps in studying its detailed biochemical properties and elucidating its role in health and disease. This knowledge may pave the way for novel strategies in treating disorders related to calcium dysregulation and ER stress.
