Analytical Data
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基因名
EPHA5
- Application
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别名
Brain-specific kinase; bsk; CEK 7; Eck like sequence 1; EHK 1; EHK-1; EK7; Els 1; EPH homology kinase 1; EPH-like kinase 7; EPHA5; EPHA5_HUMAN; Ephrin type A receptor 5; Ephrin type-A receptor 5; HEK 7; hEK7; Receptor protein tyrosine kinase HEK 7; Rek 7; TYRO 4; Tyrosine protein kinase receptor EHK 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P54756
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表达区间
595-1037aa
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氨基酸序列
SGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL
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分子量
80.68 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Ephrin type-A receptor 5 (EPHA5) is a member of the Eph receptor family, which plays a crucial role in cell signaling and communication, particularly in the context of neuronal development and tissue organization. As a receptor tyrosine kinase, EPHA5 has been implicated in various physiological processes, including synaptic plasticity, neural cell migration, and angiogenesis. Dysregulation of EPHA5 has been associated with several pathological conditions, such as cancer and neurodegenerative diseases. The production of recombinant EPHA5 proteins has become essential for studying its biological functions and interactions with ephrin ligands. By generating and purifying EPHA5 in a controlled laboratory environment, researchers can explore its signaling pathways, investigate its role in disease mechanisms, and evaluate its potential as a therapeutic target. Moreover, understanding the structure-function relationship of EPHA5 through recombinant protein studies can provide insights into its ligand-binding properties and downstream signaling cascades. This research has significant implications for developing strategies to modulate EPHA5 activity, which could lead to novel treatments for diseases where EPHA5 is involved. Overall, the study of recombinant EPHA5 proteins is a pivotal step in elucidating the complex functions of this receptor and its impact on health and disease.
