Cat: PAX2000-12802

Recombinant Human ZNF280C Protein,His

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Analytical Data

  • Gene name

    ZNF280C

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    FLJ20095; OTTHUMP00000024010; OTTHUMP00000062566; RP3-438D16.3; SUHW3; Suppressor of hairy wing homolog 3; Z280C_HUMAN; Zinc finger Protein 280C; Zinc finger Protein 633; Znf280c; ZNF633

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8ND82

  • Expression Region

    1-737 aa

  • AA Sequence

    MDDDKPFQPK NISKMAELFM ECEEEELEPW QKKVEETQDE DDDELIFVGE ISSSKPAISN ILNRGHSSSS SKGIKSEPHS PGIPEIFRTA SQRCRDPPSN PVAASPRFHL VSKSSQSSVT VENASKPDFT KNSQVGSDNS SILLFDSTQE SLPPSQDIPA IFREGMKNTS YVLKHPSTSK VNSVTPKKPK TSEDVPQINP STSLPLIGSP PVTSSQVMLS KGTNTSSPYD AGADYLRACP KCNVQFNLLD PLKYHMKHCC PDMITKFLGV IVKSERPCDE DKTDSETGKL IMLVNEFYYG RHEGVTEKEP KTYTTFKCFS CSKVLKNNIR FMNHMKHHLE LEKQNNESWE NHTTCQHCYR QYPTPFQLQC HIESTHTPHE FSTICKICEL SFETEHILLQ HMKDTHKPGE MPYVCQVCQF RSSTFSDVEA HFRAAHENTK NLLCPFCLKV SKMATPYMNH YMKHQKKGVH RCPKCRLQFL TSKEKAEHKA QHRTFIKPKE LEGLPPGAKV TIRASLGPLQ SKLPTAPFGC APGTSFLQVT PPTSQNTTAR NPRKSNASRS KTSKLHATTS TASKVNTSKP RGRIAKSKAK PSYKQKRQRN RKNKMSLALK NIRCRRGIHK CIECHSKIKD FASHFSIYIH CSFCKYNTNC NKAFVNHMMS SHSNHPGKRF CIFKKHSGTL RGITLVCLKC DFLADSSGLD RMAKHLSQRK THTCQVIIEN VSKSTSTSEP TTGCSLK

  • Molecular Weight

    83 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZNF280C, a member of the C2H2 zinc finger protein family, has garnered attention due to its potential roles in gene regulation and various cellular processes. This protein is known to be involved in transcriptional regulation, which is crucial for the proper functioning of genes that control development, differentiation, and responses to environmental stimuli. Recent research has highlighted its implications in pathological conditions, including cancer and developmental disorders, making it a target of interest for therapeutic interventions. The recombinant expression of ZNF280C allows for the detailed study of its structure and function, enabling researchers to elucidate its mechanisms of action at the molecular level. Furthermore, producing recombinant ZNF280C facilitates the exploration of its interactions with DNA and other proteins, providing insights into its role within specific biological pathways. As understanding of ZNF280C expands, it may offer new perspectives on the design of gene-based therapies and strategies to modulate its activity in disease contexts, emphasizing the importance of this research in the broader field of molecular biology and medicine.

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