Analytical Data
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Gene name
FRMPD2
- Application
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Alternative Names
FRMPD2; PDZD5C; PDZK4; PDZK5C; FERM and PDZ domain-containing protein 2; PDZ domain-containing protein 4; PDZ domain-containing protein 5C
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q68DX3
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Expression Region
1-261aa
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AA Sequence
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCDIMRLGRYSFSSPLTRLSTDIF
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Molecular Weight
55.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FRMPD2, or FERM and PDZ domain-containing protein 2, is a member of the FERM and PDZ domain-containing proteins, which play crucial roles in cellular processes such as signaling, adhesion, and cytoskeletal organization. Research surrounding FRMPD2 has gained traction due to its involvement in various physiological and pathological processes, including neuronal development, synaptic signaling, and possibly in neurodegenerative diseases. The protein’s unique structural features facilitate interactions with other signaling molecules, making it a potential target for therapeutic interventions. In recent studies, FRMPD2 has been implicated in modulating the actin cytoskeleton, indicating its critical role in maintaining cell shape and motility. Given the importance of FRMPD2 in brain function and its potential links to disease mechanisms, understanding its molecular pathways and interactions is essential. The generation of recombinant FRMPD2 protein enables detailed exploration of its structure-function relationship, providing insights into its biological roles and paving the way for novel therapeutic strategies aimed at targeting its interactions in disease contexts.
