Analytical Data
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Gene name
PDGFC
- Application
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Alternative Names
PDGFC；SCDGF；Platelet-derived growth factor C
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NRA1
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Expression Region
1-345aa
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AA Sequence
MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERII TVSTNGSIHSPRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPE DDICKYDFVEVEEPSDGTILGRWCGSGTVPGKQISKGNQIRIRFVSDEYF PSEPGFCIHYNIVMPQFTEAVSPSVLPPSALPLDLLNNAITAFSTLEDLI RYLEPERWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNLLTEEVRLYSC TPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSK VTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG
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Molecular Weight
65 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PDGFC (Platelet-Derived Growth Factor C) is a member of the PDGF family, which plays a crucial role in various biological processes, including cell proliferation, migration, and angiogenesis. Its involvement in cellular signaling pathways is critical for tissue development and repair, making it a significant focus of research in regenerative medicine and cancer therapy. Located in the extracellular matrix, PDGFC is particularly relevant in wound healing and fibrosis, as it stimulates fibroblast activation and collagen synthesis. Aberrant PDGFC signaling has been implicated in several pathological conditions, including tumors and fibrotic diseases, which has prompted investigations into its potential as a therapeutic target. Furthermore, the generation of recombinant PDGFC proteins allows for detailed studies of its mechanism of action and the development of novel interventions to modulate its activity. Understanding the qualities and functions of PDGFC through recombinant technologies can provide insights into its therapeutic applications and enhance our ability to tackle diseases associated with dysregulated PDGF pathways.
