Analytical Data
-
Gene name
GYPE
- Application
-
Alternative Names
GYPE；GPE；Glycophorin-E
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P15421
-
Expression Region
1-78aa
-
AA Sequence
MYGKIIFVLLLSGIVSISASSTTGVAMHTSTSSSVTKSYISSQTNGITLINWWAMARVIFEVMLVVVGMIILISYCIR
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GYPE, or glycophorin E, is a member of the glycophorin family of proteins, which are primarily found in the erythrocyte membrane. These proteins play critical roles in cell-cell interactions, cell membrane stability, and the modulation of immune responses. The study of GYPE and its recombinant forms has gained importance due to the protein's potential implications in understanding blood group antigen systems, particularly in relation to the MNS blood group system. GYPE exhibits significant homology with other glycophorin proteins, making it a valuable target for research into erythrocyte biology and related disorders. Recombinant GYPE proteins can be utilized to identify antibodies in transfusion medicine, explore their roles in malaria infections, and assess their potential as biomarkers for various hematological conditions. Furthermore, the expression and purification of recombinant GYPE have enabled researchers to delve into its structural and functional characteristics, enhancing our knowledge of membrane protein interactions and stability. As a result, GYPE is not only crucial for advancing transfusion science but also for broadening our understanding of cell surface glycoproteins in health and disease.
