Analytical Data
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Gene name
FZD2
- Application
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Alternative Names
Fz-2; hFz2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14332
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Expression Region
24-565aa
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AA Sequence
QFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNSRHGETTV
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Molecular Weight
62.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FZD2, or Frizzled-2, is a member of the Frizzled family of receptors that play a critical role in the Wnt signaling pathway, which is essential for various developmental processes and cellular functions, including cell proliferation, differentiation, and organogenesis. The study of FZD2 has gained prominence due to its involvement in cancer progression and various diseases, as abnormal Wnt signaling is often linked to tumorigenesis. Recent research has indicated that FZD2 might serve as a potential biomarker for certain cancers and a target for therapeutic interventions. The production of recombinant FZD2 protein enables scientists to investigate its structure, binding properties, and interactions with Wnt ligands and other cellular components. Understanding these interactions at a molecular level can provide insights into the regulatory mechanisms of the Wnt pathway and its impact on cellular behavior in health and disease. Furthermore, recombinant FZD2 proteins can be utilized in both in vitro and in vivo studies to explore their functions and therapeutic potentials in cancer treatment and regenerative medicine. Thus, the research on FZD2 recombinant proteins not only enhances our understanding of fundamental biological processes but also holds promise for developing innovative strategies in combating Wnt-related diseases.
