Analytical Data
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基因名
KRT10
- Application
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别名
K10; KRT10; KPP; Keratin 10; Epidermolytic Hyperkeratosis; Keratosis Palmaris Et Plantaris; Keratin, type I cytoskeletal 10
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种属
Human
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表达系统
E. coli
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标签
N-6His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13645
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表达区间
153-456aa
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
CK10, or Cytokeratin 10, is a crucial intermediate filament protein predominantly expressed in the epidermis and certain external epithelial tissues, playing a vital role in maintaining the structural integrity and functional properties of keratinocytes. Research on CK10 recombinant protein has gained prominence due to its significant involvement in skin health, wound healing, and various dermatological conditions. Alterations in CK10 expression are often linked to skin disorders such as psoriasis, eczema, and skin cancers, underscoring its potential as a biomarker for disease progression and therapeutic target. Recombinant CK10 is used in various studies to elucidate the mechanisms of keratinocyte differentiation and to explore its interactions with other cellular components. Moreover, the production of CK10 as a recombinant protein enables researchers to investigate its functional properties in vitro and in vivo, paving the way for novel therapeutic strategies aimed at enhancing skin regeneration and treating skin-related diseases. Understanding the biochemical properties and regulatory mechanisms of CK10 can significantly contribute to the fields of dermatology and regenerative medicine, making it a focal point of interest for scientists seeking to discover innovative approaches to enhance skin health and address various skin pathologies. Therefore, the investigation of CK10 recombinant protein not only adds to the basic understanding of epidermal biology but also holds the promise of leading to practical applications in clinical treatments for skin disorders.
