Cat: IPD-X50214

Recombinant Mouse Ccl3 Protein ,GST & His

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Analytical Data

  • 基因名

    Ccl3

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Heparin-binding chemotaxis protein;L2G25BMacrophage inflammatory protein 1-alpha ;MIP-1-alpha;SIS-alpha;Small-inducible cytokine A3TY-5

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    GST+His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P10855

  • 表达区间

    24-92aa

  • 分子量

    37 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Ccl3, also known as C-C motif chemokine 3 or macrophage inflammatory protein-1 alpha (MIP-1α), is a significant chemokine involved in immune response and inflammation. It primarily functions by recruiting monocytes, macrophages, and T-cells to sites of inflammation, playing a critical role in various pathological conditions, including chronic inflammatory diseases, infections, and tumor progression. Research on Ccl3 recombinant protein has gained traction due to its potential therapeutic applications, such as in the modulation of immune responses and the treatment of diseases where inflammation plays a key role. The production of Ccl3 as a recombinant protein allows for detailed studies on its structure, function, and interaction with receptors, providing insights into its mechanisms in immune regulation. Additionally, understanding its role in different biological contexts can lead to innovative strategies for therapeutic interventions. Recent studies have suggested that manipulating Ccl3 levels or its signaling pathways could enhance immune responses against tumors or regulate excessive inflammation. This growing body of research highlights the importance of Ccl3 recombinant protein in both fundamental immunology and clinical applications, making it a promising target for future therapeutic developments.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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