Analytical Data
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Gene name
ETV4
- Application
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Alternative Names
E1AF; PEA3
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Species
Human
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Source
E. coli
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Tag
N-His;N-StrepⅡ
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P43268-1
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Expression Region
R338-A470
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Protein Length
Partial
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Molecular Weight
18.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ETV4, a member of the E26 transformation-specific (ETS) family of transcription factors, plays a critical role in various biological processes, including cell growth, differentiation, and response to external stimuli. Due to its involvement in numerous cellular pathways, ETV4 has been implicated in several diseases, particularly in cancers such as prostate and breast cancer, where it can function as an oncogene. The study of ETV4 recombinant proteins has gained momentum in recent years, as these proteins can facilitate the investigation of the functional roles of ETV4 in cellular contexts. By producing recombinant ETV4 proteins, researchers can delve into understanding the protein’s interactions with other molecular partners, its regulatory mechanisms, and its impact on gene expression. Furthermore, the recombinant ETV4 proteins can serve as potential biomarkers for cancer diagnosis and prognosis, as well as targets for therapeutic intervention. Advances in recombinant protein technology have enabled the optimization of ETV4 protein purification and characterization, allowing for detailed functional assays. This research provides crucial insights into the molecular underpinnings of ETV4’s role in tumorigenesis, potentially leading to the development of novel therapeutic strategies aimed at modulating its activity in cancer cells. As such, the exploration of ETV4 recombinant proteins remains a vibrant area of investigation with significant implications for cancer biology and treatment.
