Analytical Data
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基因名
DHX33
- Application
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别名
DEAH box protein 33 (DDX33)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H6R0
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表达区间
1-450aa
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分子量
53.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The DHX33 protein, a member of the DExH box RNA helicase family, plays a crucial role in various cellular processes, including RNA metabolism, ribosome biogenesis, and the regulation of immune responses. It is known to participate in the unwinding of RNA structures, which is essential for effective translation and gene expression. Recent studies have highlighted its importance in viral infections, as DHX33 can recognize viral RNA, triggering immune responses such as the production of interferons. Given its potential as a therapeutic target, researchers have focused on the recombinant expression of DHX33 to investigate its structure, functional properties, and interactions with RNA and other biomolecules. Understanding the mechanistic basis of DHX33's role in health and disease could lead to novel strategies in antiviral therapies and cancer treatment, where dysregulation of RNA processing is often observed. This research aims not only to provide insights into the fundamental biological roles of DHX33 but also to explore its potential applications in biotechnology and medicine.
