Analytical Data
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基因名
BRF1
- Application
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别名
TFIIIB90 (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF)
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种属
Human
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92994
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表达区间
1-677aa
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分子量
75.3
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BRF1 (BRAF-regulated factor 1) is a crucial component of the transcriptional machinery, particularly in the context of RNA polymerase II-mediated transcription. It plays a significant role in the recruitment of transcription factors and co-activators to gene promoters. Dysregulation of BRF1 has been linked to various diseases, including cancer, where its overexpression can lead to aberrant gene expression profiles and tumorigenesis. The study of BRF1 recombinant protein has gained traction as researchers aim to elucidate its functional mechanisms and interactions with other cellular proteins. By producing and purifying BRF1 as a recombinant protein, scientists can investigate its structural properties, functional activity, and interaction networks in vitro. Furthermore, understanding the precise role of BRF1 can offer insights into normal cellular processes and the molecular basis of diseases, paving the way for potential therapeutic strategies. The ongoing research into BRF1 emphasizes the importance of post-transcriptional regulation in gene expression and highlights its potential as a biomarker or target for drug development.
