Analytical Data
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Gene name
hbhA
- Application
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Alternative Names
Adhesin
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Species
Mycobacterium tuberculosis
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P9WIP8
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Expression Region
2-199aa
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Molecular Weight
28.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HBHA (Heparin-Binding Hemagglutinin) is a surface protein found in certain pathogenic bacteria, including Mycobacterium tuberculosis. This protein plays a crucial role in bacterial adherence and colonization of host tissues, which is essential for the establishment of infection. Research into HBHA has gained traction due to its potential as a target for vaccine development, given its ability to elicit immune responses. Recombinant forms of HBHA have been produced to study its structure-function relationships, immune evasion mechanisms, and interactions with host cells. Immunological studies have demonstrated that HBHA can stimulate both humoral and cellular immune responses, making it a candidate for inclusion in multi-antigen vaccine strategies against tuberculosis. Additionally, the understanding of HBHA's role in pathogenesis has implications for developing novel therapeutic approaches. The production and characterization of recombinant HBHA not only aid in elucidating its biological functions but also enhance our understanding of bacterial pathogenicity, leading to new avenues for therapeutic and preventive measures against bacterial infections. Thus, continued research into HBHA recombinant proteins is vital for advancing infectious disease control and improving public health outcomes.
