Analytical Data
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Gene name
PEX14
- Application
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Alternative Names
NAPP2; Pex14p; Peroxin-14; PTS1 receptor-docking protein; Peroxisomal membrane anchor protein PEX14
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75381
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Expression Region
Thr31~Asp377
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Molecular Weight
60kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PEX14 is a crucial protein involved in peroxisome biogenesis and function, serving as a component of the peroxisomal import machinery. It plays a pivotal role in the docking and translocation of peroxisomal matrix proteins, which are essential for various metabolic pathways, including lipid metabolism and reactive oxygen species detoxification. Dysfunction of PEX14 has been implicated in certain peroxisomal disorders, highlighting its importance in cellular health. Recent studies have focused on elucidating the structural and functional dynamics of PEX14, as well as its interactions with other peroxins and cargo proteins. Understanding the mechanisms underlying PEX14's role in peroxisome assembly and protein import can provide insights into the pathogenesis of peroxisomal biogenesis disorders and open new avenues for therapeutic interventions in related metabolic diseases. The exploration of PEX14 not only contributes to our knowledge of organelle development and maintenance but also enhances our understanding of fundamental cellular processes related to metabolism and oxidative stress response.
