Analytical Data
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Gene name
IREM2
- Application
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Alternative Names
CD300E; CD300LE; CLM2; CD300 Antigen Like Family Member E; CMRF35-Like Molecule 2; Polymeric immunoglobulin receptor 2
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
D0V9T4
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Expression Region
Pro21~Met204
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Molecular Weight
24kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IREM2 (Immunoregulatory Receptor Expressed on Myeloid Cells 2) is a member of the immunoglobulin superfamily and plays a crucial role in the immune response modulation, particularly within myeloid cells. The study of IREM2 has gained significance due to its potential involvement in various pathological conditions, including autoimmune diseases and cancer. Research indicates that IREM2 interacts with ligands, which can influence pro-inflammatory and anti-inflammatory signaling pathways, thus affecting immune cell activation and function. Understanding the mechanisms of IREM2's action could offer new insights into immune regulation and pave the way for novel therapeutic strategies. Recent advances in protein engineering and recombinant protein technology have enabled the production of functional IREM2 proteins, facilitating detailed studies of their structure, function, and interactions. As researchers delve deeper into the role of IREM2 in modulating immune responses, there is increasing interest in targeting this receptor as a means to improve immunotherapy approaches and enhance outcomes in diseases characterized by dysregulated immune responses.
