Analytical Data
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Gene name
NRIP3
- Application
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Alternative Names
C11orf14; Sarcoma antigen NY-SAR-105
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NQ35
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Expression Region
Met1~Ala241
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Molecular Weight
33kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NRIP3 (Nuclear Receptor Interacting Protein 3), also known as SFPQ (Splicing Factor Proline- and Glutamine-rich), plays a significant role in various cellular processes, including gene expression regulation, RNA splicing, and stress responses. Research on NRIP3 has gained momentum due to its involvement in various diseases, such as cancer and neurodegenerative disorders. This protein interacts with nuclear receptors, modulating their transcriptional activity and influencing pathways critical for cell proliferation and differentiation. Given its multifunctional nature, NRIP3 is considered a potential biomarker for disease states and a target for therapeutic interventions. The study of recombinant NRIP3 has provided insights into its structural and functional properties, paving the way for understanding its biological significance. By generating recombinant NRIP3 in heterologous systems, researchers can investigate its interactions with other proteins and regulatory elements. Moreover, such studies enable the exploration of its functional mechanisms at the molecular level, thereby revealing its potential as a drug target. Understanding the nuances of NRIP3 function is essential for developing novel therapeutic strategies, particularly in the context of nuclear receptor-mediated pathways that are frequently dysregulated in various pathologies. Thus, ongoing research into NRIP3's properties and interactions is pivotal for elucidating its role in health and disease, fostering advancements in biomedical science and therapeutics.
