Analytical Data
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Gene name
ADH3
- Application
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Alternative Names
ADH1C; Alcohol dehydrogenase subunit gamma
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P00326
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Expression Region
Met1~Phe375
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Molecular Weight
43kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADH3, or Alcohol Dehydrogenase 3, is an important enzyme involved in the metabolism of alcohol in the human body, specifically known for its role in converting alcohols into aldehydes and ketones. This enzyme is part of the alcohol dehydrogenase family and is primarily expressed in the liver, where it contributes to the detoxification process. Research on ADH3 has gained momentum due to its implications in various clinical conditions, including alcoholism, liver diseases, and genetic variations affecting alcohol metabolism. Understanding the structure and function of recombinant ADH3 protein can provide insights into the mechanisms of alcohol metabolism and its associated health risks. Furthermore, studies on the recombinant form of this enzyme help in elucidating its kinetic properties and interactions with different substrates, laying the groundwork for potential therapeutic interventions. Additionally, ADH3 has implications in pharmacogenomics, where genetic polymorphisms can affect individual responses to alcohol and certain medications, thereby influencing the development of personalized medicine strategies. Overall, the exploration of ADH3 recombinant protein serves not only to advance fundamental biochemistry knowledge but also to inform clinical practices related to alcohol consumption and its health consequences.
