Analytical Data
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基因名
HNRPK
- Application
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别名
hnRNP-K; CSBP; HNRNPK; TUNP; Transformation Upregulated Nuclear Protein
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P61978
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表达区间
Met1~Phe463
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分子量
51kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNRPK, or heterogeneous nuclear ribonucleoprotein K, is a multifunctional protein that plays a crucial role in various cellular processes, including RNA processing, transcription regulation, and cell signaling. Its involvement in mRNA metabolism makes it a significant player in the post-transcriptional regulation of gene expression. Recent studies have shown that HNRPK is implicated in several pathological conditions, including cancer, where its overexpression can contribute to tumor progression and resistance to therapy. The need for a deeper understanding of HNRPK's function has led to an increased interest in the development of recombinant HNRPK proteins for research purposes. These recombinant proteins allow scientists to explore the molecular mechanisms underlying HNRPK's role in cellular activities and its interactions with other proteins and nucleic acids. By studying HNRPK in different contexts, researchers aim to elucidate its contribution to diseases, potentially paving the way for therapeutic interventions targeting its pathways. Current research focuses on the structural characterization of HNRPK, its post-translational modifications, and its interactions within ribonucleoprotein complexes, which are critical for understanding its diverse functional roles within the cell. Overall, the exploration of recombinant HNRPK is pivotal for expanding our knowledge of RNA biology and its implications in health and disease.












