Analytical Data
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Gene name
XPO4
- Application
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Alternative Names
Exp4
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9C0E2
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Expression Region
Ala881~Lys1151
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Molecular Weight
34.3kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
XPO4, or Exportin 4, is a member of the exportin family of proteins that are crucial for nucleocytoplasmic transport, a fundamental cellular process that regulates the movement of molecules between the nucleus and the cytoplasm. This protein is particularly involved in the export of specific RNA and proteins, playing a critical role in various biological processes, including gene expression, signal transduction, and cell differentiation. Recent studies have highlighted XPO4's involvement in multiple diseases, including certain types of cancer and neurodegenerative disorders, suggesting that it may serve as a potential therapeutic target. The understanding of XPO4's structure and function has been enhanced through the study of its recombinant forms, which allows researchers to investigate its mechanism of action in detail. By producing XPO4 as a recombinant protein, scientists can explore its interactions with different export cargoes and its role in the cellular transport machinery. Furthermore, studying XPO4 can provide insights into the regulation of nucleocytoplasmic transport, which is critical for maintaining cellular homeostasis. Ongoing research aims to elucidate the precise molecular mechanisms by which XPO4 operates and its implications in health and disease, potentially paving the way for novel therapeutic strategies that target XPO4-mediated pathways.
