Analytical Data
-
基因名
AP1m1
- Application
-
别名
AP47; CLAPM2; CLTNM; MU-1A; Clathrin assembly protein complex 1 mu-1 medium chain 1; Golgi adaptor HA1/AP1 adaptin mu-1 subunit; Mu1A-adaptin
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BXS5
-
表达区间
Ser2~Pro258
-
分子量
32kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AP1m1, or Adaptor Protein 1 Gamma 1, is a crucial component of the clathrin-coated vesicle (CCV) formation process, which plays a key role in intracellular trafficking and membrane dynamics. Research on AP1m1 has gained prominence due to its involvement in various cellular functions, including endocytosis, protein sorting, and signaling pathways. Mutations or dysregulation of AP1m1 have been linked to a range of diseases, including neurodegenerative disorders and certain cancers, underscoring its importance in maintaining cellular homeostasis. The reconstruction of AP1m1 protein has become a pivotal focus within molecular biology and biochemistry, enabling researchers to elucidate its structural and functional properties and understand its interactions with other proteins in the cell. Studying the recombinant form of AP1m1 allows scientists to investigate its role in the formation of AP1 complexes and clathrin-mediated transport. Furthermore, by elucidating the mechanisms of AP1m1 function, researchers aim to develop therapeutic strategies targeting its pathways, potentially leading to novel treatments for diseases associated with its malfunction. Understanding the biochemistry of AP1m1 and its role in cellular mechanisms is thus vital for identifying how its alteration can impact overall cellular function and contribute to pathologies.
