Analytical Data
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Gene name
CLSTN3
- Application
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Alternative Names
CSTN3; CDHR14; CS3; Alc-beta; Cadherin-Related Family Member 14; Alcadein-beta
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BQT9
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Expression Region
Met1~Arg227
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Molecular Weight
55kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CLSTN3 (Calsyntenin 3) is a member of the calsyntenin family of proteins, which are characterized by their roles in synaptic function and neuronal development. Recent research has highlighted the significance of CLSTN3 in the context of neurodevelopmental disorders, including autism spectrum disorder (ASD) and schizophrenia. CLSTN3 is primarily localized at excitatory synapses in the central nervous system and has been implicated in various cellular processes such as endocytosis, synapse formation, and neuronal signaling. The study of CLSTN3 recombinant proteins has become pivotal for understanding its functional mechanisms, interactions with other synaptic proteins, and its contribution to neuronal pathologies. By generating and analyzing recombinant CLSTN3, researchers aim to elucidate its structure-function relationship, explore its role in synaptic plasticity, and assess the consequences of genetic mutations on its functionality. This line of investigation holds promise for unveiling potential therapeutic targets for treating neurodevelopmental disorders associated with dysregulated synaptic function.
