Analytical Data
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基因名
ABI1
- Application
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别名
ABI-1; E3B1; NAP1BP; SSH3BP1; Spectrin SH3 Domain Binding Protein 1; Abelson interactor 1; Abl-binding protein 4; Nap1-binding protein; Eps8 SH3 domain-binding protein
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IZP0
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表达区间
Met1~Pro182
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分子量
24kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ABI1, or Abl interactor 1, is a critical protein involved in various cellular processes, including cell signaling, growth, and differentiation. It primarily functions as a regulator of the Abl tyrosine kinase, which is essential for proper cell function and development. Aberrant signaling of Abl is implicated in several diseases, including cancer, making ABI1 a significant focus of research. Studies have shown that ABI1 interacts with multiple signaling pathways, influencing actin cytoskeleton dynamics and cell motility. Given its role in cellular regulation and potential implications in pathological conditions, recombinant ABI1 protein has become crucial for understanding its function and interactions at a molecular level. Researchers have been employing recombinant DNA technology to produce ABI1 protein for biochemical assays, structural studies, and to elucidate its role in cellular processes. By exploring the biochemical properties and interactions of ABI1, scientists aim to uncover therapeutic targets for diseases associated with dysregulated Abl signaling. The study of ABI1 not only provides insights into fundamental cellular mechanisms but also contributes to the broader understanding of oncogenesis and cellular behavior in response to external stimuli.
