Analytical Data
-
Gene name
ABCC10
- Application
-
Alternative Names
MRP7; SIMRP7; Multidrug Resistance Associated Protein 7
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q5T3U5
-
Expression Region
Val1246~Pro1492
-
Molecular Weight
30kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABCC10, also known as ATP-binding cassette sub-family C member 10, is a member of the ATP-binding cassette (ABC) transporters, which are integral membrane proteins involved in the transport of various molecules across cellular membranes. Research on ABCC10 has garnered significant attention due to its role in drug resistance, particularly in cancer therapy. It has been identified as a potential mediator of the efflux of chemotherapeutic agents, thereby contributing to the reduced efficacy of cancer treatments. Several studies have linked ABCC10 expression levels to clinical outcomes in cancer patients, highlighting its importance in understanding resistance mechanisms. Additionally, ABCC10 is involved in the transport of various endogenous substrates, including certain lipids and xenobiotics, suggesting its broader physiological relevance. The investigation into the recombinant expression of ABCC10 protein allows for a deeper understanding of its structure-function relationships, transport mechanisms, and potential as a therapeutic target. Expanding the knowledge on ABCC10 could pave the way for novel strategies to overcome drug resistance in cancer therapy, enhancing the effectiveness of existing treatments and improving patient outcomes. Consequently, the study of ABCC10 is not only crucial for cancer research but also for developing innovative approaches to manage drug resistance in various diseases.
