Analytical Data
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基因名
Mxd1
- Application
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别名
Protein MAD (Mad) (Mad1) (Max dimerizer 1)
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种属
Mouse
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表达系统
Baculovirus
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P50538
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表达区间
1-227aa
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分子量
29.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Mxd1, also known as Mnt or Mad3, is a member of the Myc/Max/Mxd transcription factor network, which plays a crucial role in regulating cell growth, differentiation, and apoptosis. Research into Mxd1 has garnered attention due to its involvement in various biological processes and diseases, particularly cancer. The protein acts as a transcriptional repressor, antagonizing the activity of oncogenic Myc, thus maintaining cellular homeostasis. Dysregulation of Mxd1 expression and function can contribute to tumorigenesis, making it a potential therapeutic target. Investigating the structural and functional properties of Mxd1 can provide insights into its mechanisms of action, and its interactions with other proteins and DNA elements. Moreover, studies focusing on the recombination and purification of Mxd1 can facilitate the development of inhibitors or modulators for therapeutic purposes. Understanding the precise role of Mxd1 in cellular signaling pathways and its impact on gene expression profiles is vital for unraveling the complexities of cancer biology and exploring novel treatment strategies. The recombinant production of Mxd1 as a model system can also aid in elucidating its biochemical characteristics and potential regulatory functions within the Myc network, opening new avenues for research aimed at improving cancer therapies.
