Analytical Data
-
Gene name
pyrG
- Application
-
Alternative Names
Cytidine 5'-triphosphate synthase Cytidine triphosphate synthetase
-
Species
Streptococcus pyogenes serotype M1
-
Source
E. coli
-
Tag
N- His-SUMO & C- Myc
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P65925
-
Expression Region
1-267aa
-
Molecular Weight
49.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PyrG is a crucial gene in various organisms, including bacteria and fungi, that plays a significant role in the regulation of pyrimidine metabolism. It encodes a protein involved in the synthesis of pyrimidine nucleotides, which are essential building blocks for DNA and RNA synthesis. The study of PyrG and its recombinant protein has gained attention due to its potential applications in biotechnology and medicine. By understanding the structure and function of PyrG, researchers aim to elucidate the mechanisms of pyrimidine biosynthesis and its regulation, which could lead to new strategies for combating diseases linked to nucleotide imbalances. Moreover, recombinant PyrG can serve as a valuable tool in genetic engineering, enabling the manipulation of metabolic pathways for the production of nucleotides and their derivatives. This research can also contribute to the development of targeted therapies, as dysregulation of pyrimidine metabolism is associated with various cancers and metabolic disorders. Therefore, investigating the properties and functionality of recombinant PyrG is essential for both fundamental biological research and practical applications in health and industry.
