Analytical Data
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Gene name
DCTN3
- Application
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Alternative Names
Dynactin complex subunit 22KDA subunit ;p22
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75935
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Expression Region
2-176aa
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Molecular Weight
35.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DCTN3, or Dynactin subunit 3, is a critical component of the dynactin complex, which plays a pivotal role in intracellular transport, particularly in the movement of organelles, vesicles, and chromosomes. Research on DCTN3 has garnered interest due to its significant involvement in cellular processes and its potential implications in neurodegenerative diseases and cancer. Mutations or dysregulation of DCTN3 have been associated with various pathological conditions, highlighting its importance in maintaining cellular health and function. The study of recombinant DCTN3 protein allows researchers to investigate its structure, function, and interactions with other cellular molecules in vitro. This research can provide insights into the molecular mechanisms underlying cellular transport and reveal how alterations in DCTN3 activity may contribute to disease states. Additionally, understanding the functional dynamics of DCTN3 through recombinant protein studies can pave the way for developing therapeutic strategies targeting dynactin-related pathways. Overall, the exploration of DCTN3 and its recombinant protein lays the groundwork for elucidating the complexities of cellular transport mechanisms and their relevance in health and disease.
