Analytical Data
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Gene name
GOSR2
- Application
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Alternative Names
27KDA Golgi SNARE protein;Membrin
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14653
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Expression Region
1-190aa
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Molecular Weight
38.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GOSR2, also known as Golgi reassembly-stacking protein 2, is a crucial component of the Golgi apparatus, playing an essential role in protein transport and the maintenance of Golgi structure. Research into GOSR2 has gained interest due to its involvement in various cellular processes, including the formation of COPII-coated vesicles and the mediation of intra-Golgi transport. Mutations in the GOSR2 gene are linked to several pathological conditions, such as developmental disorders and neurological diseases, highlighting its importance in maintaining cellular homeostasis. Studies have shown that GOSR2 is significant for the proper functioning of the secretory pathway, impacting the transport of proteins to their destinations within and outside the cell. Furthermore, GOSR2 interacts with other important proteins, influencing Golgi dynamics and cellular signaling pathways. Thus, understanding the structure-function relationship of GOSR2 and its mechanism in vesicular transport is vital for elucidating its role in health and disease. Ongoing research aims to explore the therapeutic potential of targeting GOSR2-related pathways, making it a promising candidate for drug development in treating various disorders linked to Golgi dysfunction.
