Analytical Data
-
Gene name
HAPLN4
- Application
-
Alternative Names
Brain link protein 2 (BRAL2) (KIAA1926)
-
Species
Human
-
Source
E. coli
-
Tag
N- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q86UW8
-
Expression Region
30-402aa
-
Molecular Weight
43.7 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HAPLN4 (Hyaluronan and Proteoglycan Link Protein 4) is a member of the HAPLN family, which is characterized by its role in connecting hyaluronan and proteoglycans in the extracellular matrix (ECM). Research has highlighted the importance of HAPLN4 in various physiological and pathological processes, including development, tissue maintenance, and inflammation. It is predominantly expressed in the nervous system, where it has been implicated in neural development and synaptic formation. Abnormal HAPLN4 expression has been linked to several neurological disorders, suggesting its potential role as a biomarker or therapeutic target. Recent studies have also focused on the role of HAPLN4 in regulating the ECM environment, which is crucial for cell signaling and tissue integrity. By investigating the biochemical properties and functional roles of HAPLN4, researchers aim to elucidate its mechanisms of action and contribution to cellular processes. Understanding HAPLN4’s interactions with other ECM components and its influence on cell behavior may provide insights into novel treatment strategies for diverse conditions, including neurodegenerative diseases and cancer. The production of recombinant HAPLN4 protein has become essential for these studies, enabling in vitro assays and functional analyses that are critical to advancing our knowledge of its biological significance.
