Analytical Data
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基因名
HNRNPA3
- Application
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别名
hnRNP A3(HNRPA3)
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51991
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表达区间
1-378aa
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分子量
46.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNRNPA3, a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, plays a significant role in various RNA processing events, including splicing, transport, and stability. Its involvement in cellular mechanisms has made it a focal point in the study of gene regulation and expression. Recent research has highlighted the importance of HNRNPA3 in numerous biological processes, such as cell proliferation, differentiation, and response to stress. Abnormal expression or mutations of HNRNPA3 have been linked to various diseases, including cancer, neurodegenerative disorders, and certain autoimmune conditions. Given its pivotal functions, the development of recombinant HNRNPA3 proteins is essential for elucidating its molecular mechanisms and interactions within the cell. By expressing and purifying HNRNPA3, researchers aim to investigate its role in RNA metabolism and its potential as a therapeutic target. The recombinant protein allows for the exploration of HNRNPA3's structural and functional properties, paving the way for advancements in understanding its contribution to health and disease. This background underpins ongoing studies focused on employing recombinant HNRNPA3 in biochemical assays, structural biology, and potential therapeutic applications, ultimately striving to delineate its roles in cellular dynamics and disease pathways.
